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When adverse factors disrupt the brains homeostatic repair mechanisms, physiological aging may progress to pathological aging, ultimately leading to neuronal loss and neurodegeneration (Park and Reuter-Lorenz, 2009

FFA-induced adipocyte inflammation and insulin resistance: Involvement of ER stress and IKKbeta pathways

Given that a plant-based diet may also be effective for managing menopausal symptoms, researchers decided to combine the two: a plant-based diet plus whole soybeans